Micro-Injected Collagen - LipFusion Color Shine The next generation of lip plumpers has arrived. LipFusion is moisturizing treatment gloss infused with revolutionary technology to plump lips instantly, no kidding. How it works: Tiny, dehydrated, marine collagen microspheres are instantly absorbed by the lips, and seek out the body's natural moisture. As soon as the spheres become re-hydrated, they plump and hold onto the moisture they've collected, creating a mild "swelling" of the lip tissue. The result is fuller, smoother, perfectly plumped lips in seconds. Results can last for up to 48 hours.